I am comfortable working in MAYA or CINEMA 4D with sub divided polygons for hard surface modeling.
For character design or anything organic I’m a big fan of ZBRUSH. I work on a cintiq whenever possible as this gives me the freedom of clay modeling which I have done for recreation all my life.
I tend towards painting textures in zbrush, if I have time I’ll jump into MARI.
In LOS ANGELES during my MFA in Production Design I created card and CG models of existing and fantasy structures working with the director and cinematographer to achieve the best use of space for lighting and action.